Article
Rat vascular smooth muscle cells immortalized with SV40 large T antigen possess defined smooth muscle cell characteristics including growth inhibition by heparin.
Journal of cellular physiology - 1 Feb 1990
Reilly C F
Abstract excerpt
Rat aortic smooth muscle cells (SMC) have been established by retroviral delivery of the complementary DNA (cDNA) for the simian virus 40 large T antigen (SV40LT) and examined for SMC phenotypic markers and growth characteristics, including responsiveness to the antiproliferative effects of hepar...
Topics
- Actins
- Animals
- Antigens, Polyomavirus Transforming
- Aorta, Abdominal
- Blood
- Cell Division
- Cell Line, Transformed
- DNA
- Fluorescent Antibody Technique
- Gene Expression
- Genetic Vectors
- Heparin
- Muscle, Smooth, Vascular
- Phenotype
- Rats
- Rats, Inbred Strains
- Rats, Nude
- Retroviridae