Article
Isolation of vascular smooth muscle cell cultures with altered responsiveness to the antiproliferative effect of heparin.
Journal of cellular physiology - 1 May 1996
Caleb B L, Hardenbrook M, Cherington V, Castellot J J
Abstract excerpt
Smooth muscle cell (SMC) hyperplasia in the arterial wall is an important component of both atherogenesis and post-vascular surgical restenosis. One naturally-occurring group of molecules which can suppress SMC proliferation in animal models and in cell culture systems are the complex carbohydrat...
Topics
- Adenovirus E1A Proteins
- Animals
- Antigens, Polyomavirus Transforming
- Blotting, Western
- Cell Division
- Cells, Cultured
- Dose-Response Relationship, Drug
- Drug Resistance
- Fibrinolytic Agents
- Genes, myc
- Genetic Vectors
- Growth Inhibitors
- Heparin
- Muscle, Smooth, Vascular
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Retroviridae
