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Article

Isolation of vascular smooth muscle cell cultures with altered responsiveness to the antiproliferative effect of heparin.

Journal of cellular physiology - 1 May 1996

Caleb B L, Hardenbrook M, Cherington V, Castellot J J

Abstract excerpt

Smooth muscle cell (SMC) hyperplasia in the arterial wall is an important component of both atherogenesis and post-vascular surgical restenosis. One naturally-occurring group of molecules which can suppress SMC proliferation in animal models and in cell culture systems are the complex carbohydrates of the heparan sulfate class, including heparin. In this communication, we have used retrovirus vectors to introduce...

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PMID: 8613458
DOI: 10.1002/(SICI)1097-4652(199605)167:2<185::AID-JCP1>3.0.CO;2-L

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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