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Article

p59fyn-p125FAK cooperation in development of CD4+CD8+ thymocytes.

Blood - 1 Feb 1996

Kanazawa S, Ilić D, Hashiyama M, Noumura T, Yamamoto T, Suda T, Aizawa S

Abstract excerpt

p59fyn is an Src family nonreceptor tyrosine kinase that has been suggested to play an important role in T-cell development and function. p125FAK is a unique nonreceptor tyrosine kinase and has been known to respond to integrin-extracellular matrix interactions. To examine their roles in thymocytes, heterozygous fak mutation was introduced into homozygous Fyn deficiency. The double mutation, but neither Fyn...

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PMID: 8562954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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