p59fyn-p125FAK cooperation in development of CD4+CD8+ thymocytes.

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Article

p59fyn-p125FAK cooperation in development of CD4+CD8+ thymocytes.

Blood - 1 Feb 1996

Kanazawa S, Ilić D, Hashiyama M, Noumura T, Yamamoto T, Suda T, Aizawa S

Abstract excerpt

p59fyn is an Src family nonreceptor tyrosine kinase that has been suggested to play an important role in T-cell development and function. p125FAK is a unique nonreceptor tyrosine kinase and has been known to respond to integrin-extracellular matrix interactions. To examine their roles in thymocyt...

Topics

Animals
Atrophy
Base Sequence
CD4 Antigens
CD8 Antigens
Cell Adhesion Molecules
Cell Differentiation
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Genotype
Mice
Mice, Knockout
Molecular Sequence Data
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-fyn
T-Lymphocyte Subsets
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 8562954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8562954-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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