Article
Identification of a cdk-activating kinase in fission yeast.
The EMBO journal - 15 Dec 1995
Buck V, Russell P, Millar J B
Abstract excerpt
We have identified a second cyclin-dependent kinase (cdk) in fission yeast, crk1, which encodes a 335 amino acid protein that is most closely related to the KIN28 gene product from Saccharomyces cerevisiae and to a cdk activating kinase (CAK) encoded by the MO15 gene from Xenopus laevis, crk1 is essential for viability and delta crk1 cells arrest with septa and condensed chromatin. We show that Crk1 associates...
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