Article
Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant.
Molecular and biochemical parasitology - 30 Oct 1998
Wang Y, Dimitrov K, Garrity L K, Sazer S, Beverley S M
Abstract excerpt
Cell cycle control by cdc2-related kinases (CRKs) is essential to the regulation of cell proliferation and developmental processes in many organisms. Alternating phases of growth, arrest, and differentiation are characteristics of the infectious cycle of many trypanosomatid parasites, raising the...
Topics
- Amino Acid Sequence
- Animals
- CDC2 Protein Kinase
- Catalytic Domain
- Cosmids
- Cyclin-Dependent Kinases
- Gene Expression
- Genes, Protozoan
- Leishmania major
- Molecular Sequence Data
- Mutation
- Protein Kinases