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Article

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.

Molecular and cellular biology - 1 Oct 1995

Sterner D E, Lee J M, Hardin S E, Greenleaf A L

Abstract excerpt

Saccharomyces cerevisiae CTDK-I is a protein kinase complex that specifically and efficiently hyperphosphorylates the carboxyl-terminal repeat domain (CTD) of RNA polymerase II and is composed of three subunits of 58, 38, and 32 kDa. The kinase is essential in vivo for normal phosphorylation of the CTD and for normal growth and differentiation. We have now cloned the genes for the two smaller kinase subunits,...

Topics

Amino Acid Sequence
Base Sequence
Cloning, Molecular
Cold Temperature
Cyclin-Dependent Kinases
Cyclins
Genes, Fungal
Molecular Sequence Data
Mutation
Protein Kinases
Restriction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 7565723
DOI: 10.1128/MCB.15.10.5716
PMCID: PMC230822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7565723-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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