Article
A rice homolog of Cdk7/MO15 phosphorylates both cyclin-dependent protein kinases and the carboxy-terminal domain of RNA polymerase II.
The Plant journal : for cell and molecular biology - 1 Dec 1998
Yamaguchi M, Umeda M, Uchimiya H
Abstract excerpt
The activation of cyclin-dependent protein kinases (CDKs) requires phosphorylation of a threonine residue within the T-loop by a CDK-activating kinase (CAK). The R2 protein of rice is very similar to CAKs of animals and fission yeast at the amino acid level but phosphorylation by R2 has not yet been demonstrated. When R2 was overexpressed in a CAK-deficient mutant of budding yeast, it suppressed the temperature...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.