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Article

The genomic instability of yeast cdc6-1/cdc6-1 mutants involves chromosome structure and recombination.

Molecular & general genetics : MGG - 1 Nov 1995

Bruschi C V, McMillan J N, Coglievina M, Esposito M S

Abstract excerpt

When diploid cells of Saccharomyces cerevisiae homozygous for the temperature-sensitive cell division cycle mutation cdc6-1 are grown at a semipermissive temperature they exhibit elevated genomic instability, as indicated by enhanced mitotic gene conversion, mitotic intergenic recombination, chromosomal loss, chromosomal gain, and chromosomal rearrangements. Employing quantitative Southern analysis of chromosomes...

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PMID: 8552037
DOI: 10.1007/BF00290230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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