Article
The genomic instability of yeast cdc6-1/cdc6-1 mutants involves chromosome structure and recombination.
Molecular & general genetics : MGG - 1 Nov 1995
Bruschi C V, McMillan J N, Coglievina M, Esposito M S
Abstract excerpt
When diploid cells of Saccharomyces cerevisiae homozygous for the temperature-sensitive cell division cycle mutation cdc6-1 are grown at a semipermissive temperature they exhibit elevated genomic instability, as indicated by enhanced mitotic gene conversion, mitotic intergenic recombination, chro...
Topics
- Blotting, Southern
- Cell Cycle Proteins
- Chromosomes, Fungal
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genotype
- Mitosis
- Mutagenesis
- Phenotype
- Recombination, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature
