Article

A phylogenetically-restricted essential cell cycle progression factor in the human pathogen <i>Candida albicans</i>

2021-09-23

Abstract excerpt

Chromosomal instability in fungal pathogens caused by cell division errors is associated with antifungal drug resistance. To identify mechanisms underlying such instability and to uncover new potential antifungal targets, we conducted an overexpression screen monitoring chromosomal stability in the human fungal pathogen Candida albicans . Analysis of ~1000 genes uncovered six chromosomal stability (CSA) genes, fi...

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Literature Corpus work: 9d9fb331-e4b8-5c53-80b7-8173df8961cb
DOI: 10.1101/2021.09.23.461448

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