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Article

Apparent uncoupling of oncogenicity from fibroblast transformation and apoptosis in a mutant myc gene transduced by feline leukemia virus.

Journal of virology - 1 Feb 1996

Fulton R, Gallagher R, Crouch D, Neil J C

Abstract excerpt

The T17 v-myc oncogene was transduced by feline leukemia virus in a spontaneous feline T-cell lymphosarcoma. Molecular cloning and sequencing of the v-myc gene revealed several unique mutations, including a large deletion affecting amino acids 49 to 124 and a 3-bp insertion within the basic DNA binding domain which converts Leu-362 to Phe-Arg. The T17 lymphoma cell line was found to express a truncated 50-kDa Myc...

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Identifiers

PMID: 8551576
DOI: 10.1128/JVI.70.2.1154-1162.1996
PMCID: PMC189924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Apparent uncoupling of oncogenicity from fibroblast transformation and apoptosis in a mutant myc gene transduced by feline leukemia virus.PMID 8551576Read ↗

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A 3' truncation of myc caused by chromosomal translocation in a human T-cell leukemia is tumorigenic when tested in established rat fibroblasts.Semantic proximity Read ↗

MYC levels govern hematopoietic tumor type and latency in transgenic mice.Semantic proximity Read ↗

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The chicken HMG-17 gene is dispensable for cell growth in vitro.Semantic proximity Read ↗

Identification of Downstream-Initiated c-Myc Proteins Which Are Dominant-Negative Inhibitors of Transactivation by Full-Length c-Myc ProteinsSemantic proximity Read ↗

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