Article
Lymphokines modulate the growth and survival of thymic tumor cells containing a novel feline leukemia virus/Notch2 variant.
Veterinary immunology and immunopathology - 20 Sept 1999
Linenberger M L, Rohn J L, Deng T, Ellis-Smith S, Ingber R, Overbaugh J
Abstract excerpt
Tumorigenesis occurs through a multistep process initiated by genetic lesions and facilitated by endogenous and external growth/survival signals. In many malignancies, specific oncogenic mutations correlate with phenotypic characteristics, inferring lineage-specific pathogenic mechanisms. To characterize these relationships in a unique feline tumor, we studied primary cells and two-cell lines...
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