Detection of p53 gene alteration in renal-cell cancer by micropreparation techniques of tumor specimens.

doi:10.1002/ijc.2910640609

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Detection of p53 gene alteration in renal-cell cancer by micropreparation techniques of tumor specimens.

International journal of cancer - 20 Dec 1995

Kuczyk M A, Serth J, Bokemeyer C, Jonassen J, Arndt H, Paeslack U, Werner M, Tan H K, Jonas U

Abstract excerpt

Alterations in the p53 tumor-suppressor gene have been identified in a variety of human malignancies, including renal-cell cancer. A technique for the isolation of tumor areas from tissue specimens to analyze formalin-fixed and paraffin-embedded tumors and try to avoid a disturbance of the results due to genetic background signal by the presence of tumor-infiltrating lymphocytes, was established. The presence of...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Base Sequence
Carcinoma, Renal Cell
Exons
Female
Gene Deletion
Genetic Markers
Humans
Kidney Neoplasms
Male
Middle Aged
Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 8550242
DOI: 10.1002/ijc.2910640609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Point Mutation

Regression Analysis