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Article

Microdissection as a means to verify allelic imbalance in tumour biology samples.

Anticancer research - 1 Jan 2000

Speiser P, Gharehbaghi-Schnell E, Schneeberger C, Eder S, Zeillinger R

Abstract excerpt

Allelotypes (TP53, AFM051xd10 and alu-i1) in normal DNA and in DNA from paraffin-embedded tumours of a patient with a p53 germ-line mutation were compared in order to demonstrate LOH. Microdissection was applied in order to overcome difficulties with the interpretation of LOH data from a pelvic recurrence of a primary malignant histiocytoma. Furthermore, a rapid and simple boiling method was developed in order to...

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PMID: 8615654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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