Article
Genetic polymorphism of xenobiotic metabolising enzymes in Slovenian lung cancer patients.
Pflugers Archiv : European journal of physiology - 1 Jan 2000
Dolzan V, Rudolf Z, Breskvar K
Abstract excerpt
Most carcinogenic substances require metabolic activation in order to become ultimate carcinogens. Genetic polymorphism of xenobiotic metabolising enzymes cytochromes P450 may therefore influence human cancer susceptibility. The aim of our study was to investigate if CYP1A1 gene polymorphism contributes to lung cancer susceptibility in Slovenian patients. Two polymorphic sites in CYP1A1 gene were analysed in DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
