Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer.

doi:10.1093/carcin/14.6.1085

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Article

Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer.

Carcinogenesis - 1 Jun 1993

Kawajiri K, Nakachi K, Imai K, Watanabe J, Hayashi S

Abstract excerpt

The p53 tumor suppressor gene is mutated in diverse types of human cancer, and the normal allele encodes a nuclear protein that regulates expression of cell cycle-related genes as a transcription factor. The wild-type of p53 protein exists as at least two forms of variants among human populations...

Topics

Adenocarcinoma
Base Sequence
Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Codon
Cytochrome P-450 Enzyme System
Female
Genes, p53
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Male
Molecular Sequence Data
Phenotype
Polymerase Chain Reaction
Polymorphism, Genetic
Risk

Source

Open in PubMed

Identifiers

PMID: 8389669
DOI: 10.1093/carcin/14.6.1085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8389669-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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