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Article

Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer.

Carcinogenesis - 1 Jun 1993

Kawajiri K, Nakachi K, Imai K, Watanabe J, Hayashi S

Abstract excerpt

The p53 tumor suppressor gene is mutated in diverse types of human cancer, and the normal allele encodes a nuclear protein that regulates expression of cell cycle-related genes as a transcription factor. The wild-type of p53 protein exists as at least two forms of variants among human populations, ascribed to amino acid replacement at codon 72 of Arg by Pro. In this study, we show that this germ line Arg-Pro...

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PMID: 8389669
DOI: 10.1093/carcin/14.6.1085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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