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Article

Immunoreactivity for p53 and mdm2 and the detection of p53 mutations in human malignant mesothelioma.

Virchows Archiv : an international journal of pathology - 1 Jan 1995

Segers K, Backhovens H, Singh S K, De Voecht J, Ramael M, Van Broeckhoven C, Van Marck E

Abstract excerpt

Previous immunohistochemical studies on malignant mesothelioma with antibodies recognizing both the wild and the mutant types of the p53 protein have shown immunoreactivity in 25-70% of cases. This study was designed to determine whether there is immunoreactivity for p53 and mdm2 protein in malignant mesothelioma and to correlate p53 expression with the detection of mutations in p53 at DNA level. In 10 of 15...

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Identifiers

PMID: 8548129
DOI: 10.1007/BF00199393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Immunoreactivity for p53 and mdm2 and the detection of p53 mutations in human malignant mesothelioma.PMID 8548129Read ↗

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