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Article

Analysis of p53 and mdm2 proteins in malignant fibrous histiocytoma in absence of gene alteration: prognostic significance.

Virchows Archiv : an international journal of pathology - 1 Dec 1999

Molina P, Pellín A, Navarro S, Boix J, Carda C, Llombart-Bosch A

Abstract excerpt

TP53 and MDM2 genes and their protein expression were evaluated in frozen and paraffin-embedded tissue from 27 patients with malignant fibrous histiocytoma to elucidate the relationship between them, their implication in tumor progression mechanisms and their possible diagnostic-prognostic value in malignant fibrous histiocytoma. Single-strand conformation polymorphism analysis and direct sequencing of polymerase...

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Source

Identifiers

PMID: 10628802
DOI: 10.1007/s004280050446

Genes

MDM2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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