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Article

High levels of MDM2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines.

British journal of cancer - 1 Nov 1996

Ungar S, Van de Meeren A, Tammilehto L, Linnainmaa K, Mattson K, Gerwin B I

Abstract excerpt

Prior analysis of 20 human mesothelioma cell lines for p53 status revealed only two mutations and one p53 null cell line, although p53 expression was detected in most cell lines. In addition, mRNA and protein expression of the retinoblastoma gene product in human mesothelioma cell lines is similar to normal controls. We have tested for p53 induction after exposure to ionising radiation and demonstrate this...

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Share to DNA, Neoplasm
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Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8932331
DOI: 10.1038/bjc.1996.585
PMCID: PMC2074839

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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