P53 expression in Reed-Sternberg cells does not correlate with gene mutations in Hodgkin's disease.

doi:10.1093/ajcp/106.6.728

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Article

P53 expression in Reed-Sternberg cells does not correlate with gene mutations in Hodgkin's disease.

American journal of clinical pathology - 1 Dec 1996

Elenitoba-Johnson K S, Medeiros L J, Khorsand J, King T C

Abstract excerpt

Immunohistochemically detectable p53 protein expression is common in the Reed-Sternberg and Hodgkin's (RS-H) cells of Hodgkin's disease, but p53 gene mutations have only rarely been identified. The authors found p53 expression in RS-H cells in 16 of 30 cases of Hodgkin's disease (53%), with the p...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, Viral
Child
DNA Primers
DNA, Neoplasm
Female
Gene Expression
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Genes, Immunoglobulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, p53

Herpesvirus 4, Human

Hodgkin Disease

Humans

Immunoenzyme Techniques

Ki-67 Antigen

Source

Open in PubMed

Identifiers

PMID: 8980348
DOI: 10.1093/ajcp/106.6.728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8980348-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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P53 expression in Reed-Sternberg cells does not correlate with gene mutations in Hodgkin's disease.PMID 8980348Read ↗

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