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Article

mdm2-P2 transcript levels predict the functional activity of the p53 tumor suppressor in primary leukemic cells.

Oncogene - 30 Apr 1998

Bull E K, Chakrabarty S, Brodsky I, Haines D S

Abstract excerpt

The mdm2-P2 promoter is a transcriptional target of the p53 tumor suppressor. The aim of this study was to determine if there is an association between the level of these transcripts and the status of the p53 gene in human leukemic cells. A correlation between mdm2-P2 transcript levels and p53 gene status was observed in all cell lines examined. Primary malignant cells from 10 leukemic patients were also analysed...

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Source

Identifiers

PMID: 9619834
DOI: 10.1038/sj.onc.1201757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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