Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor.

doi:10.1016/s0091-6749(95)70195-8

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Article

Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor.

The Journal of allergy and clinical immunology - 1 Dec 1995

Muto A, Watanabe S, Itoh T, Miyajima A, Yokota T, Arai K

Abstract excerpt

The high-affinity and functional granulocyte-macrophage colony-stimulating factor receptor (GMR) is composed of two distinct subunits, alpha and beta; and the cytoplasmic domain of the beta subunit is essential to transduce growth-promoting signals. In contrast to the beta subunit, the role of the alpha subunit is not well characterized. We examined the requirement of the cytoplasmic domain of the alpha subunit...

Topics

3T3 Cells
Amino Acid Sequence
Animals
Cell Division
Cytoplasm
Gene Expression Regulation
Granulocyte-Macrophage Colony-Stimulating Factor
Humans
Macromolecular Substances
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phosphorylation

Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

Recombinant Fusion Proteins

Sensitivity and Specificity

Signal Transduction

Transfection

Source

Open in PubMed

Identifiers

PMID: 8543767
DOI: 10.1016/s0091-6749(95)70195-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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