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Article

Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation.

Molecular and cellular biology - 1 Dec 1993

Dong F, van Buitenen C, Pouwels K, Hoefsloot L H, Löwenberg B, Touw I P

Abstract excerpt

The granulocyte colony-stimulating factor receptor (G-CSF-R) transduces signals important for the proliferation and maturation of myeloid progenitor cells. To identify functionally important regions in the cytoplasmic domain of the G-CSF-R, we compared the actions of the wild-type receptor, two mutants, and a natural splice variant in transfectants of the mouse pro-B cell line BAF3 and two myeloid cell lines, 32D...

Topics

Animals
Base Sequence
Cell Differentiation
Cell Division
Cell Line
Cytoplasm
DNA, Complementary
Genetic Variation
Granulocytes
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Receptors, Granulocyte Colony-Stimulating Factor

Signal Transduction

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 8246993
DOI: 10.1128/mcb.13.12.7774-7781.1993
PMCID: PMC364849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8246993-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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