Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation.

Molecular and cellular biology - 1 Dec 1993

Dong F, van Buitenen C, Pouwels K, Hoefsloot L H, Löwenberg B, Touw I P

Abstract excerpt

The granulocyte colony-stimulating factor receptor (G-CSF-R) transduces signals important for the proliferation and maturation of myeloid progenitor cells. To identify functionally important regions in the cytoplasmic domain of the G-CSF-R, we compared the actions of the wild-type receptor, two mutants, and a natural splice variant in transfectants of the mouse pro-B cell line BAF3 and two myeloid cell lines, 32D...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Division

Share to Cell Line

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 8246993
DOI: 10.1128/mcb.13.12.7774-7781.1993
PMCID: PMC364849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation.PMID 8246993Read ↗

Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines.Semantic proximity Read ↗

Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor.Semantic proximity Read ↗

Functional domains of the granulocyte colony-stimulating factor receptor.Semantic proximity Read ↗

Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation.Semantic proximity Read ↗

Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors.Semantic proximity Read ↗

Inhibition of granulocyte-macrophage colony-stimulating factor receptor function by a splice variant of the common beta-receptor subunit.Semantic proximity Read ↗

Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells.Semantic proximity Read ↗

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease.Semantic proximity Read ↗

A point mutation in the granulocyte colony-stimulating factor receptor (G-CSF-R) gene in a case of acute myeloid leukemia results in the overexpression of a novel G-CSF-R isoformSemantic proximity Read ↗

Novel variant isoform of G-CSF receptor involved in induction of proliferation of FDCP-2 cells: relevance to the pathogenesis of myelodysplastic syndrome.Semantic proximity Read ↗

Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more.Semantic proximity Read ↗

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.