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Article

Identification of two regions within the cytoplasmic domain of the human interferon-gamma receptor required for function.

The Journal of biological chemistry - 15 Oct 1991

Farrar M A, Fernandez-Luna J, Schreiber R D

Abstract excerpt

Functionally active human interferon-gamma (IFN gamma) receptors require the presence of at least two polypeptides: the IFN gamma receptor and an accessory molecule encoded by a gene on human chromosome 21. Here we have used a murine L cell line that stably contains human chromosome 21 (SCC16-5) to determine whether the receptor's cytoplasmic domain is important for receptor function. SCC16-5 stably transfected...

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PMID: 1717469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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