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Article

Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly.

The Journal of biological chemistry - 26 Nov 1999

Haman A, Cadieux C, Wilkes B, Hercus T, Lopez A, Clark S, Hoang T

Abstract excerpt

The granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor (GMR) is composed of two chains that belong to the superfamily of cytokine receptors typified by the growth hormone receptor. A common structural element found in cytokine receptors is a module of two fibronectin-like domains, each characterized by seven beta-strands denoted A-G and A'-G', respectively. The alpha-chain (GMRalpha) confers low...

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Identifiers

PMID: 10567387
DOI: 10.1074/jbc.274.48.34155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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