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Article

p16/INK4a gene methylation is a frequent finding in pulmonary MALT lymphomas at diagnosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2005

Takino Hisashi, Okabe Mitsukuni, Li Chunmei, Ohshima Koichi, Yoshino Tadashi, Nakamura Shigeo, Ueda Ryuzo, Eimoto Tadaaki, Inagaki Hiroshi

Abstract excerpt

p16/INK4a gene alterations have been associated with tumor progression in lymphoid malignancies. However, their significance in mucosa-associated lymphoid tissue (MALT) lymphoma is unclear. We investigated p16 gene methylation and mutation in a large series of untreated cases of pulmonary MALT lymphoma and diffuse large B-cell lymphoma (DLBL), and correlated p16 gene alterations with a MALT lymphoma-specific...

Read the complete abstract on PubMed

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Share to DNA Methylation
Share to Genes, p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell

Share to Lymphoma, B-Cell, Marginal Zone

Share to Lymphoma, Large B-Cell, Diffuse

Share to Oncogene Proteins, Fusion

Share to Polymorphism, Single-Stranded Conformational

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 15832193
DOI: 10.1038/modpathol.3800400

Genes

MALT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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