Article
Replication error phenotype and p53 gene mutation in lymphomas of mucosa-associated lymphoid tissue.
The American journal of pathology - 1 Feb 1996
Peng H, Chen G, Du M, Singh N, Isaacson P G, Pan L
Abstract excerpt
Low grade mucosa-associated lymphoid tissue (MALT) lymphomas commonly arise from a background of chronic inflammatory lesions and can transform into high grade tumors at a late stage. Because chronic inflammation is closely associated with genetic instability, which is one of the mechanisms leading to activation of oncogenes and inactivation of tumor suppressor genes, it is possible that genetic instability plays...
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