Article
Genetic abnormalities during transition from Helicobacter-pylori-associated gastritis to low-grade MALToma.
Lancet (London, England) - 7 Jan 1995
Calvert R, Randerson J, Evans P, Cawkwell L, Lewis F, Dixon M F, Jack A, Owen R, Shiach C, Morgan G J
Abstract excerpt
The helicobacter-associated transition from chronic gastritis to MALToma (lymphoma of mucosa-associated lymphoid tissue) may require genetic change in the host. We have studied gastrectomy specimens from twelve cases of primary B-cell gastric lymphoma showing evidence of chronic gastritis and low...
Topics
- Alleles
- Cell Transformation, Neoplastic
- Chronic Disease
- Gastritis
- Genes, APC
- Genes, DCC
- Genes, Tumor Suppressor
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Lymphoma, B-Cell, Marginal Zone
- Polymerase Chain Reaction
- Precancerous Conditions
- Stomach Neoplasms
