Article
Genetic abnormalities during transition from Helicobacter-pylori-associated gastritis to low-grade MALToma.
Lancet (London, England) - 7 Jan 1995
Calvert R, Randerson J, Evans P, Cawkwell L, Lewis F, Dixon M F, Jack A, Owen R, Shiach C, Morgan G J
Abstract excerpt
The helicobacter-associated transition from chronic gastritis to MALToma (lymphoma of mucosa-associated lymphoid tissue) may require genetic change in the host. We have studied gastrectomy specimens from twelve cases of primary B-cell gastric lymphoma showing evidence of chronic gastritis and low-grade or high-grade MALToma to look for allele imbalance at microsatellites for six tumour-suppressor genes. We...
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