Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BCL10 gene mutation in lymphoma.

Blood - 15 Jun 2000

Du M Q, Peng H, Liu H, Hamoudi R A, Diss T C, Willis T G, Ye H, Dogan A, Wotherspoon A C, Dyer M J, Isaacson P G

Abstract excerpt

BCL10 is directly involved in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. Wild-type BCL10 promoted apoptosis and suppressed malignant transformation in vitro, whereas truncated mutants lost the pro-apoptotic activity and exhibited gain of function enhancement of transformation. We studied 220 lymphomas for genomic BCL10 mutation by polymerase chain reaction-single-strand conformational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Exons
Share to Lymphoma, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell, Marginal Zone

Share to Lymphoma, T-Cell

Share to Neoplasm Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Deletion

Source

Identifiers

PMID: 10845924

Genes

BCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BCL10 gene mutation in lymphoma.PMID 10845924Read ↗

Infrequent BCL10 mutations in B-cell non-Hodgkin's lymphomas.Semantic proximity Read ↗

Screening for mutations of Bcl10 in leukaemia.Semantic proximity Read ↗

Bcl10 expression, rearrangement and mutation in MALT lymphoma: correlation with expression of nuclear factor-kappaB.Semantic proximity Read ↗

BCL10 somatic mutations rarely occur in gastric lymphoma: detection of high frequency of polymorphisms in BCL10 coding region.Semantic proximity Read ↗

Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).Semantic proximity Read ↗

Low frequency of BCL10 gene mutations in B-cell non-Hodgkin's lymphoma.Semantic proximity Read ↗

BCL10 gene mutations rarely occur in lymphoid malignancies.Semantic proximity Read ↗

Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.Semantic proximity Read ↗

Significance of Bcl10 gene mutations in the clinical diagnosis of MALT-type ocular adnexal lymphoma in the Chinese population.Semantic proximity Read ↗

Absence of Bcl10 gene mutations in Ewing's sarcomas.Semantic proximity Read ↗

BCL10 is not the gene inactivated by mutation in the 1p22 deletion region in mantle cell lymphoma.Semantic proximity Read ↗

MALT Lymphoma : Recent Advances in Aetiology and Molecular GeneticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.