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Article

Different human interleukin-4 mutants preferentially activate human or murine common receptor gamma chain.

European journal of biochemistry - 15 Nov 1995

Lischke A, Kammer W, Friedrich K

Abstract excerpt

Interleukin-4 (IL-4) shows species-specific activity due to species-restricted interaction with the IL-4 receptor alpha (IL-4R alpha) chain. The second subunit of a functional IL-4 receptor, the common gamma chain (gamma c), is more promiscuous, since human IL-4 is able to activate IL-4 receptor complexes containing either human or murine common gamma receptor chain (gamma c). We have stably transfected...

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Identifiers

PMID: 8529628
DOI: 10.1111/j.1432-1033.1995.100_c.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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