Article
[Microsatellite instability: a potential tool for the study of life sciences].
Sheng li ke xue jin zhan [Progress in physiology] - 1 Oct 1999
Ding Y, Tong T J
Abstract excerpt
Microsatellites are simply repeated nucleotide sequences scattered throughout the human genome. They are highly polymorphic among human population and inherited in a stable manner. The microsatellite instability (MI) is highly polymorphic, which is associated with the defects in DNA mismatch repair genes. MI has been widely used by scientists to study the tumorigenesis. On the basis of their findings, a "mutator...
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