Article
Functional and molecular characterization of African swine fever virus mutants resistant to phosphonoacetic acid.
Virology - 1 Dec 1995
Marques M I, Costa J V
Abstract excerpt
African swine fever virus (ASFV) growth and plaque formation were inhibited by phosphonoacetic acid (PAA) concentrations of 200 micrograms/ml or more. One spontaneous mutant and two mutants isolated from mutagenized virus were resistant to PAA inhibition and showed practically normal viral DNA sy...
Topics
- African Swine Fever Virus
- Amino Acid Sequence
- Animals
- Antiviral Agents
- Base Sequence
- Chlorocebus aethiops
- DNA, Viral
- DNA-Directed DNA Polymerase
- Drug Resistance, Microbial
- Genes, Viral
- Genetic Markers
- Humans
- Molecular Sequence Data
- Mutation
- Phosphonoacetic Acid
- Sequence Homology, Amino Acid
- Vero Cells
