Article
Involvement of the reparative DNA polymerase Pol X of African swine fever virus in the maintenance of viral genome stability in vivo.
Journal of virology - 1 Sept 2013
Redrejo-Rodríguez Modesto, Rodríguez Javier M, Suárez Cristina, Salas José, Salas María L
Abstract excerpt
The function of the African swine fever virus (ASFV) reparative DNA polymerase, Pol X, was investigated in the context of virus infection. Pol X is a late structural protein that localizes at cytoplasmic viral factories during DNA replication. Using an ASFV deletion mutant lacking the Pol X gene, we have shown that Pol X is not required for virus growth in Vero cells or swine macrophages under one-step growth...
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