Isolation and characterization of TK-deficient mutants of African swine fever virus.

doi:10.1016/0168-1702(94)00098-w

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Article

Isolation and characterization of TK-deficient mutants of African swine fever virus.

Virus research - 1 Apr 1995

Martín Hernández A M, Camacho A, Prieto J, Menéndez del Campo A M, Tabarés E

Abstract excerpt

African swine fever virus induces the synthesis of thymidine kinase (TK) in BHK TK-negative cells as an immediate early protein. The TK gene is not essential for growth of ASFV in cell culture and a stable viral strain deficient in TK has been isolated (E70NTKp). The genetic lesion of this ASFV T...

Topics

African Swine Fever Virus
Animals
Base Sequence
Cell Line
Cricetinae
DNA Primers
Molecular Sequence Data
Mutation
Thymidine Kinase

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