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Article

Molecular analysis of C3 allotypes in patients with nephritic factor.

Clinical and experimental immunology - 1 Mar 1993

Finn J E, Mathieson P W

Abstract excerpt

The autoantibody nephritic factor (NeF) leads to complement consumption in vivo and is associated with type II mesangiocapillary glomerulonephritis (MCGN II) and partial lipodystrophy (PLD). The third component of complement (C3) exists in two common allotypic forms, C3S and C3F, distinguished at the protein level by electrophoresis. An increased frequency of the rarer C3F allele has been reported in several...

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Identifiers

PMID: 8443964
DOI: 10.1111/j.1365-2249.1993.tb05917.x
PMCID: PMC1554701

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