Article
Expression and tissue localization of donor-specific complement C3 synthesized in human renal allografts.
European journal of immunology - 1 Apr 1995
Andrews P A, Finn J E, Lloyd C M, Zhou W, Mathieson P W, Sacks S H
Abstract excerpt
Recent evidence suggests that the third component of complement, C3, is synthesized in renal tissue, and that increased C3 synthesis occurs in allograft rejection and immune complex-mediated nephritis. However, it is unclear whether intrinsic renal cells or migratory cells in the inflammatory infiltrate, possibly of recipient bone marrow origin, are the source of the C3 detected. This was investigated by...
Topics
- Alleles
- Base Sequence
- Complement C3
- DNA, Complementary
- Graft Rejection
- Humans
- Kidney
- Kidney Transplantation
- Molecular Sequence Data
- Polymerase Chain Reaction
- RNA, Messenger