Article
Molecular analysis of C3 allotypes in patients with systemic vasculitis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 1994
Finn J E, Zhang L, Agrawal S, Jayne D R, Oliveira D B, Mathieson P W
Abstract excerpt
The third component of complement (C3) exists in two main allotypic forms, C3S and C3F, distinguished at the DNA level by a single base change. An increased frequency of the rarer C3F allele has been reported in patients with the autoantibody nephritic factor and in several other autoimmune condi...
Topics
- Alleles
- Base Sequence
- Complement C3
- DNA
- DNA Primers
- Female
- Gene Frequency
- Humans
- Male
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Vasculitis