Article
Molecular analysis of C3 allotypes in Chinese patients with immunoglobulin A nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Apr 1994
Finn J E, Li P K, Lai K N, Mathieson P W
Abstract excerpt
The third component of complement (C3) exists in two main allotypic forms, C3S and C3F. An increased frequency of the rarer C3F allele has been reported in several autoimmune conditions, including immunoglobulin A nephropathy (IgAN), in white patients. C3F is known to be rare in the Chinese population, but C3 allotypes have not been studied in Chinese patients with IgAN. The molecular basis of the S/F...
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