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Article

Difference in potential DNA methylation impact on gene expression between fast- and slow-type myofibers.

Physiological genomics - 1 Feb 2021

Oe Mika, Ojima Koichi, Muroya Susumu

Abstract excerpt

Skeletal muscles are comprised of two major types of myofibers, fast and slow. It is hypothesized that once myofiber type is determined, muscle fiber-type specificity is maintained by an epigenetic mechanism, however, this remains poorly understood. To address this, we conducted a comprehensive CpG methylation analysis with a reduced representation of bisulfite sequencing (RRBS). Using GFP-myh7 mouse, we visually...

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Identifiers

PMID: 33459151
DOI: 10.1152/physiolgenomics.00099.2020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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