Article
Biological assays for Ras transformation.
Methods in enzymology - 1 Jan 1995
Clark G J, Cox A D, Graham S M, Der C J
Abstract excerpt
The rodent fibroblast systems described above have provided sensitive and rapid biological assays to characterize the properties of normal and mutated Ras proteins. Furthermore, these assays have provided in vitro systems to measure the ability of other cellular components to modulate Ras signal transduction and transformation. However, while these assays provide an excellent measure of Ras-transforming activity,...
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