A complex of the signal sequence binding protein and the SRP RNA promotes translocation of nascent proteins.

doi:10.1002/j.1460-2075.1995.tb00235.x

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Article

A complex of the signal sequence binding protein and the SRP RNA promotes translocation of nascent proteins.

The EMBO journal - 15 Nov 1995

Hauser S, Bacher G, Dobberstein B, Lütcke H

Abstract excerpt

Translocation of proteins across the endoplasmic reticulum membrane is initiated by the signal recognition particle (SRP), a cytoplasmic ribonucleoprotein complex consisting of a 7S RNA and six polypeptides. To investigate the functions of the SRP components, we have tested the activities of seve...

Topics

Animals
Biological Transport
Cytosol
Guanosine Triphosphate
Humans
Intracellular Membranes
Microsomes
Mutation
Protein Binding
Protein Sorting Signals
RNA, Small Nuclear
Recombinant Proteins
Signal Recognition Particle

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