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Article

Catechol O-methyltransferase pharmacogenetics: photoaffinity labelling and western blot analysis of human liver samples.

Pharmacogenetics - 1 Apr 1993

Aksoy S, Klener J, Weinshilboum R M

Abstract excerpt

The level of catechol O-methyltransferase (COMT) activity and COMT thermal stability in human tissue are controlled by a common genetic polymorphism. We studied individual hepatic biopsy samples shown previously to have phenotypically high, low or intermediate COMT activities and thermal stabilit...

Topics

Affinity Labels
Blotting, Western
Catechol O-Methyltransferase
Electrophoresis, Polyacrylamide Gel
Genotype
Humans
Liver
Polymorphism, Genetic
S-Adenosylmethionine

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8518836
DOI: 10.1097/00008571-199304000-00008

Genes

COMT
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8518836-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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