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Article

Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas.

Journal of the National Cancer Institute - 7 Jul 1993

Shibata D, Schaeffer J, Li Z H, Capella G, Perucho M

Abstract excerpt

BACKGROUND: Previous molecular genetics studies of colorectal cancer have identified multiple mutations in the c-K-ras gene (also known as KRAS2) in all phases of its development. Because of technical difficulty, prior studies rarely focused attention on the detailed distribution of c-K-ras mutations in multiple regions of the same primary tumor specimen. However, with recent development of the selective UV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8515492
DOI: 10.1093/jnci/85.13.1058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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