Article
Genetic heterogeneity in sporadic colorectal adenomas.
The Journal of pathology - 1 Mar 1997
Saraga E, Bautista D, Dorta G, Chaubert P, Martin P, Sordat B, Protiva P, Blum A, Bosman F, Benhattar J
Abstract excerpt
The majority of colorectal cancers develop from adenomatous polyps under the influence of factors that are still poorly understood. Tumourigenesis is generally considered a multistep process in which multiple genetic alterations occur, eventually reflected in abnormalities of the cellular DNA content. Macroscopical features such as tumour size and tumour architecture (tubular, tubulovillous, or villous) are...
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