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Article

Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology.

British journal of cancer - 1 Jun 1993

Cawkwell L, Bell S M, Lewis F A, Dixon M F, Taylor G R, Quirke P

Abstract excerpt

In order to investigate allele loss in colorectal tumours we have developed a rapid technique which overcomes most of the problems associated with radioactive Restriction Fragment Length Polymorphism (RFLP) analysis of allele loss. We utilise microsatellite length polymorphisms which are highly informative and are closely linked to loci of interest. Sequences containing microsatellites can be amplified from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8512811
DOI: 10.1038/bjc.1993.236
PMCID: PMC1968523

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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