Article
Colony stimulating factor-1 in the induction of lupus nephritis.
Kidney international - 1 May 1993
Bloom R D, Florquin S, Singer G G, Brennan D C, Kelley V R
Abstract excerpt
In this study we examine the role of colony stimulating factor-1 (CSF-1) in the induction of lupus nephritis. The purpose of the study was to establish the relationship of CSF-1 to the prominent influx of macrophages (M phi) in the glomeruli of MRL-lpr mice with autoimmune lupus nephritis. The kidneys of MRL-lpr mice were examined before (< 12 weeks of age) and after (> 12 weeks of age) renal injury for CSF-1...
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