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Article

Granulocyte-colony stimulating factor treatment of lupus autoimmune disease in MRL-lpr/lpr mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1999

Zavala F, Masson A, Hadaya K, Ezine S, Schneider E, Babin O, Bach J F

Abstract excerpt

G-CSF not only functions as an endogenous hemopoietic growth factor for neutrophils, but also displays pro-Th2 and antiinflammatory properties that could be of therapeutic benefit in autoimmune settings. We evaluated the effect of treatment with G-CSF in a murine model of spontaneous systemic lupus erythematosus, a disease in which G-CSF is already administered to patients to alleviate neutropenia, a common...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10528219

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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