Article
Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses.
The American journal of pathology - 1 Sept 2011
Alikhan Maliha A, Jones Christina V, Williams Timothy M, Beckhouse Anthony G, Fletcher Anne L, Kett Michelle M, Sakkal Samy, Samuel Chrishan S, Ramsay Robert G, Deane James A, Wells Christine A, Little Melissa H, Hume David A, Ricardo Sharon D
Abstract excerpt
Colony-stimulating factor (CSF)-1 controls the survival, proliferation, and differentiation of macrophages, which are recognized as scavengers and agents of the innate and the acquired immune systems. Because of their plasticity, macrophages are endowed with many other essential roles during development and tissue homeostasis. We present evidence that CSF-1 plays an important trophic role in postnatal organ...
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