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Article

Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII

1 Jun 1993

Abstract excerpt

Coagulation factor VIII (FVIII) is a cofactor in the intrinsic pathway of blood coagulation for which deficiency results in the bleeding disorder hemophilia A. FVIII contains a domain structure of A1-A2-B-A3-C1-C2 of which the B domain is dispensable for procoagulant activity in vitro. In this report, we compare the properties of B-domain-deleted FVIII (residues 760 through 1639, designated LA-VIII) to wildtype...

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Share to Blood Coagulation and Thrombosis Mechanisms
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Source

Identifiers

PMID: 8499631
DOI: 10.1182/blood.v81.11.2925.2925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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