Article
Generation of cytotoxic T lymphocytes from peripheral blood.
Surgery - 1 May 1993
McKinnon J G, Lalani A, Sy L, Bear H D
Abstract excerpt
BACKGROUND: Cytotoxic T lymphocytes (CTL) have been shown to be useful for adoptive immunotherapy in malignancy. Traditional sources for CTL, such as tumor-infiltrating lymphocytes, have limitations. It would therefore be useful to develop a method of generating antitumor CTL from a renewable source such as peripheral blood. METHODS: DBA/2 mice were injected intradermally in the abdominal wall with the murine...
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