Article
Generation of cytotoxic T lymphocytes from peripheral blood.
Surgery - 1 May 1993
McKinnon J G, Lalani A, Sy L, Bear H D
Abstract excerpt
BACKGROUND: Cytotoxic T lymphocytes (CTL) have been shown to be useful for adoptive immunotherapy in malignancy. Traditional sources for CTL, such as tumor-infiltrating lymphocytes, have limitations. It would therefore be useful to develop a method of generating antitumor CTL from a renewable sou...
Topics
- Animals
- Cell Division
- Female
- Immunotherapy, Adoptive
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Liver Neoplasms
- Lymphocyte Culture Test, Mixed
- Mast-Cell Sarcoma
- Mice
- Mice, Inbred DBA
- Mitomycin
- Neoplasm Transplantation
- Phenotype
- T-Lymphocytes, Cytotoxic
- Tumor Cells, Cultured