Article
Establishment and characterization of a bank of cytotoxic T lymphocytes for immunotherapy of epstein-barr virus-associated diseases.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000
Wilkie Gwen M, Taylor Clare, Jones Marie M, Burns David M, Turner Marc, Kilpatrick David, Amlot Peter L, Crawford Dorothy H, Haque Tanzina
Abstract excerpt
Adoptive immunotherapy using Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes (CTL) generated ex vivo can be an effective treatment of EBV-positive posttransplantation lymphoproliferative disease (PTLD). We describe the establishment of a cryopreserved repository of allogeneic virus-specific CTL lines, to our knowledge the first of its kind in the world. CTL lines were grown by weekly stimulation with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
